Contents

This website contains the short course “Co-data learning: the group-regularized ridge and elastic net”

Preparation

Please install the packages GRridge:

source("https://bioconductor.org/biocLite.R")
biocLite("BiocInstaller") # if it asks to update packages, type n
biocLite("BiocGenerics") # if it asks to update packages, type n
install.packages(c("devtools", "foreach", "curl", "Matrix"))
library(devtools)
install_github("markvdwiel/GRridge")

and gren:

library(devtools)
install_version("Rcpp", version = "0.12.14", repos = "http://cran.us.r-project.org")
# R might have to restart when installing Rcpp
library(devtools)
install.packages("plyr")
install_github("magnusmunch/gren") # if it asks to install Rtools, accept 
# you might have to run the previous line again after installation of Rtools

If you encounter any problems, please don’t hesitate to contact m.munch@vumc.nl or mark.vdwiel@vumc.nl

Data

The data for the GRridge part of the practical are included in the package

The data files for the gren part of the practical are found here:

Cervical cancer data

Colorectal cancer data

Fitted models cervical cancer data

Fitted models colorectal cancer data

Practicals including Exercises

The practicals are found here:

GRridge

gren

Slides

Slides on Methodology:

Co-Data learning with empirical Bayes: GRridge and gren

GRridge extensions

gren slides

Evaluation form

form